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Dermatology & Trichology Compounding

Medically reviewed by: Vitthia Rama Murti, BPharm Hons (University of Cyberjaya), RPh 15632 — Chief of Staff & Compounding Pharmacist, Lynnity Compounding Pharmacy.
Last reviewed: 27 May 2026.

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Compounded dermatology and hair-loss treatments in Kuala Lumpur

Lynnity formulates custom dermatology and hair-loss compounds for dermatologists, aesthetic physicians, and trichologists across Malaysia. The strength of compounding is precision: we can combine actives the patient’s skin needs, in the exact concentrations the prescriber specifies, in a base suited to their skin type.

Common dermatology compounds

Acne

  • Topical clindamycin + benzoyl peroxide + retinoid (Kligman-style) — single combined cream improves compliance vs three separate products.
  • Spironolactone topical solution for hormonal jaw-line acne.
  • Tretinoin (0.025% – 0.1%) in non-irritating bases for sensitive skin.

Melasma & pigmentation

  • Modified Kligman formula: hydroquinone 4% + tretinoin 0.05% + hydrocortisone 1%.
  • Tranexamic acid 5% topical cream.
  • Cysteamine 5% cream for melasma resistant to hydroquinone.
  • Azelaic acid 15–20% formulations.

Eczema & dermatitis

  • Custom-strength hydrocortisone (0.5%, 1%, 2.5%) in moisturising bases.
  • Pimecrolimus / tacrolimus in tailored vehicles.
  • Anti-itch creams: pramoxine + menthol + camphor compounded for personal tolerance.

Psoriasis

  • Calcipotriol + clobetasol or betamethasone compound (Daivobet-style) at custom strengths.
  • LCD (liquor carbonis detergens) 5–10% in cream or ointment.
  • Methotrexate topical formulations (specialist supervision required).

Rosacea

  • Metronidazole 0.75% / 1% gel in non-comedogenic bases.
  • Ivermectin 1% cream.
  • Brimonidine 0.5% gel for erythema.

Scar revision

  • Silicone-based gels with added imiquimod or 5-fluorouracil for hypertrophic scars (specialist prescription).
  • Onion extract + silicone gels.

Anti-ageing

  • Tretinoin + niacinamide + vitamin C serums.
  • Topical bakuchiol 1–2% for tretinoin-intolerant patients.

Hair loss management — see dedicated page

For androgenetic alopecia, telogen effluvium, and alopecia areata, see our dedicated page: /services/dermatology-compounding/hair-loss-management/.

Why compounded vs OTC topical?

Off-the-shelf dermatology products are formulated for the average patient. A compound is formulated for one patient. A dermatologist may want:

  • Higher tretinoin than the 0.05% commercial maximum.
  • A specific combination not available off-the-shelf (e.g., hydroquinone + tretinoin + hydrocortisone in one cream rather than three).
  • A different vehicle — gel instead of cream for oily skin; ointment instead of cream for atopic dermatitis.
  • An excipient-free version — no fragrance, no propylene glycol, no parabens.
  • A specific pH or osmolality for sensitive or compromised skin.

Our process

  1. Dermatologist sends prescription specifying actives, concentrations, vehicle, and total quantity.
  2. Our pharmacist confirms compatibility (some actives are incompatible — e.g., hydroquinone + benzoyl peroxide oxidises rapidly).
  3. We compound under controlled humidity and light to protect light-sensitive actives like tretinoin and hydroquinone.
  4. The product is dispensed in opaque, airless packaging to maximise shelf-life.

Stability and storage

We dispense compounded dermatology products with realistic beyond-use dates (BUDs) based on USP <795> default rules and any in-house stability data. Most aqueous topical compounds are 30-day BUDs; anhydrous (oil/ointment) formulations are 90 days. Store in a cool, dark place. Some compounds require refrigeration — we will tell you on the label.

Frequently asked questions

Can Lynnity compound a hydroquinone + tretinoin cream for melasma?

Yes. A modified Kligman formula (hydroquinone 4% + tretinoin 0.05% + hydrocortisone 1%) is one of our most-prescribed dermatology compounds for melasma. It requires a dermatologist’s prescription and is usually used for 8–12 weeks with a 4-week break.

Do I need a doctor’s prescription for compounded dermatology products?

Yes for any compound containing a prescription-only ingredient (tretinoin, hydroquinone, hydrocortisone, antibiotics, calcineurin inhibitors, etc.). Cosmetic-grade compounds without scheduled actives can be dispensed without prescription.

How long do compounded creams last?

USP <795> default beyond-use dates: 30 days for aqueous formulations, 90 days for water-free (anhydrous) preparations. Some preserved products have stability data supporting longer BUDs — we mark the exact BUD on every label.

Can you make a fragrance-free or paraben-free version of my prescription?

Yes. We can formulate fragrance-free, paraben-free, sulphate-free, propylene-glycol-free and dye-free versions on prescriber request.

How do I know the compound is sterile / safe?

Topical dermatology compounds are non-sterile but compounded under controlled-environment conditions per USP <795>. Random batches are sent to an accredited third-party laboratory for microbial limit testing.